Phenacetin's 62-44-2 analgesic effects are due to its actions on the sensory tracts of the spinal cord.
In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope.
It is an antipyretic, acting on the brain to decrease the temperature set point.
It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.
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